Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PDE9A | O76083 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ABL2 | P42684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25649309 | 1.00 | BTK (0.41) | BTKEPHX2PDE9AKMT2AMAPT | |
| SCHEMBL21903703 | 0.93 | CYP1A2 (0.38) | BTKEPHX2PDE9AKMT2AMAPT | |
| SCHEMBL20645567 | 0.92 | BTK (0.41) | BTKEPHX2PDE9AKMT2AMAPT | |
| SCHEMBL15913949 | 0.92 | BTK (0.41) | BTKEPHX2PDE9AKMT2AMAPT | |
| SCHEMBL15913950 | 0.92 | BTK (0.41) | BTKEPHX2PDE9AKMT2AMAPT | |
| SCHEMBL31684304 | 0.92 | BTK (0.41) | BTKEPHX2PDE9AKMT2AMAPT | |
| SCHEMBL31684324 | 0.92 | BTK (0.41) | BTKEPHX2PDE9AKMT2AMAPT | |
| SCHEMBL25230106 | 0.91 | KMT2A (0.42) | BTKPDE9AKMT2AMAPTDPP7 | |
| SCHEMBL30497632 | 0.91 | KMT2A (0.42) | BTKPDE9AKMT2AMAPTDPP7 | |
| SCHEMBL30813541 | 0.89 | BTK (0.46) | BTKPDE9ASRCABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118696041-A | Macrocyclic BTK inhibitors | 克罗斯费尔肿瘤学控股有限公司 | 2024-09-24 | — | — | CN | disclosed |