Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31125791 | 0.93 | BTK (0.41) | TSHREPHX2P2RX3BTKMAPT | |
| SCHEMBL25649309 | 0.93 | BTK (0.41) | TSHREPHX2P2RX3BTKMAPT | |
| SCHEMBL21903794 | 0.91 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL30813465 | 0.88 | RET (0.40) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL22902838 | 0.87 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL22902474 | 0.85 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL20645567 | 0.84 | BTK (0.41) | TSHRALDH1A1EPHX2P2RX3BTK | |
| SCHEMBL24651144 | 0.84 | NPC1 (0.43) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL30497632 | 0.84 | KMT2A (0.42) | TSHRALDH1A1BTKMAPTKDM4C | |
| SCHEMBL25230106 | 0.84 | KMT2A (0.42) | TSHRALDH1A1BTKMAPTKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653626-A1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-05-20 | — | — | EP | disclosed |
| US-20200140432-A1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2020-05-07 | — | — | US | disclosed |
| CN-110914266-A | Novel 1H-pyrazolopyridine derivative and pharmaceutical composition comprising the same | 株式会社大熊制药 | 2020-03-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140432-A1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | PDCD11, G6PC1, PPM1D | CYP1A2 722/4885CYP3A4 408/4885CYP2C19 924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.