Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 3/20 | 0.41 |
| ▸ | CDC25A | P30304 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24844947 | 0.84 | TBXAS1 (1.00) | TBXAS1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL30106700 | 0.83 | TBXAS1 (0.62) | TBXAS1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL15698107 | 0.82 | TBXAS1 (0.70) | TBXAS1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL30106679 | 0.81 | TBXAS1 (0.61) | TBXAS1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL30106634 | 0.81 | TBXAS1 (0.61) | TBXAS1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL7912380 | 0.81 | TBXAS1 (0.69) | TBXAS1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL5810540 | 0.80 | TBXAS1 (0.62) | TBXAS1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL30106651 | 0.79 | TBXAS1 (0.58) | TBXAS1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL12761935 | 0.78 | TBXAS1 (0.60) | TBXAS1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL29906409 | 0.78 | TBXAS1 (0.60) | TBXAS1MAPTALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279184-A1 | HETEROAROMATIC ANALOGUES OF 3-BENZYLMENADIONE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | UNIVERSITE DE HAUTE ALSACE (FR) | 2024-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279184-A1 | HETEROAROMATIC ANALOGUES OF 3-BENZYLMENADIONE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CYP1B1, CYP1A1, CYP2B6 | TBXAS1 415/4885MAPT 4195/4885ALDH1A1 524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.