Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.47 |
| ▸ | HK1 | P19367 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29747247 | 0.86 | TBXAS1 (0.75) | TBXAS1TDP1L3MBTL1 | |
| SCHEMBL2715544 | 0.86 | TBXAS1 (0.75) | TBXAS1TDP1L3MBTL1 | |
| SCHEMBL31127526 | 0.84 | TBXAS1 (0.73) | TBXAS1RAB9AKMT2AAPAF1HKDC1 | |
| Hydrochloric Acid SCHEMBL594558 | 0.84 | TBXAS1 (0.73) | TBXAS1TDP1L3MBTL1 | |
| SCHEMBL15698107 | 0.83 | TBXAS1 (0.70) | TBXAS1RAB9AKMT2AAPAF1HKDC1 | |
| SCHEMBL7912380 | 0.82 | TBXAS1 (0.69) | TBXAS1RAB9AKMT2AAPAF1HKDC1 | |
| SCHEMBL16067092 | 0.81 | TBXAS1 (0.68) | TBXAS1ALDH1A1MAPTHTTLMNA | |
| SCHEMBL5810540 | 0.78 | TBXAS1 (0.62) | TBXAS1RAB9AKMT2AAPAF1ALDH1A1 | |
| SCHEMBL30106700 | 0.77 | TBXAS1 (0.62) | TBXAS1RAB9AKMT2AAPAF1HKDC1 | |
| SCHEMBL30106669 | 0.77 | TBXAS1 (0.62) | TBXAS1RAB9AKMT2AAPAF1HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983385-B1 | NAPHTHOQUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS | PTC THERAPEUTICS INC (US) | 2023-08-30 | — | — | EP | disclosed |
| US-20230002324-A1 | NAPHTHOQUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS | PTC THERAPEUTICS, INC. | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002324-A1 | NAPHTHOQUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS | NFE2L2, AIFM2, GPX4 | TBXAS1 924/4885RAB9A 1357/4885KMT2A 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.