Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727317 | 0.79 | CUL4A (0.45) | MKNK1MKNK2CHRNB2CHRNA4CDK1 | |
| SCHEMBL31128199 | 0.78 | MKNK1 (0.40) | MKNK1MKNK2CDK1ADORA2AADORA1 | |
| SCHEMBL18149378 | 0.77 | HDAC6 (0.51) | MKNK1MKNK2CDK1ADORA2AADORA1 | |
| SCHEMBL18150064 | 0.77 | HDAC6 (0.51) | MKNK1MKNK2CDK1ADORA2AADORA1 | |
| SCHEMBL18149381 | 0.77 | HDAC6 (0.51) | MKNK1MKNK2CDK1ADORA2AADORA1 | |
| SCHEMBL14778806 | 0.73 | CHRNB2 (0.47) | MKNK1MKNK2CHRNB2CHRNA4ADORA2A | |
| SCHEMBL15205316 | 0.73 | MKNK1 (0.44) | MKNK1MKNK2CDK1ADORA2AADORA1 | |
| SCHEMBL21812384 | 0.73 | MKNK1 (0.44) | MKNK1MKNK2CDK1ADORA2AADORA1 | |
| SCHEMBL14778803 | 0.73 | CHRNB2 (0.47) | MKNK1MKNK2CHRNB2CHRNA4ADORA2A | |
| SCHEMBL24269736 | 0.71 | FFAR1 (0.39) | MKNK1MKNK2CDK1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024166131-A1 | HETEROARYL COMPOUNDS AS PKMYT1 INHIBITORS | SATYARX PHARMA INNOVATIONS PRIVATE LIMITED (IN) | 2024-08-15 | — | — | WO | disclosed |