Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728093 | 0.82 | CHRNB4 (0.41) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL17111542 | 0.81 | CUL4A (0.50) | CUL4ACHRNB4CHRNA3HDAC6ADORA3 | |
| SCHEMBL17111487 | 0.81 | CUL4A (0.50) | CUL4ACHRNB4CHRNA3HDAC6ADORA3 | |
| SCHEMBL31128243 | 0.79 | MKNK1 (0.40) | HDAC6ADORA3ADORA2AADORA1MKNK1 | |
| SCHEMBL31727985 | 0.76 | PDE10A (0.38) | IRAK4 | |
| SCHEMBL31727516 | 0.75 | PDE10A (0.32) | SMN1; SMN2 | |
| SCHEMBL31727796 | 0.74 | MAPT (0.46) | SMN1; SMN2 | |
| SCHEMBL31727712 | 0.74 | MAPT (0.42) | SMN1; SMN2 | |
| SCHEMBL31727353 | 0.74 | MAPT (0.44) | — | |
| SCHEMBL21835451 | 0.72 | ALDH1A1 (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025231561-A1 | TERTIARY AMINE-SUBSTITUTED BIPYRIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND THEIR USE AS PHARMACEUTICALS | UNIVERSITE DE MONTREAL (CA) | 2025-11-13 | — | — | WO | disclosed |