Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31128457 | 1.00 | EPHX2 (0.46) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL21801247 | 0.80 | ALDH1A1 (0.42) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL17891790 | 0.79 | AGTR2 (0.46) | ALDH1A1MAPTNPSR1HSD17B10AGTR2 | |
| SCHEMBL17891789 | 0.79 | AGTR2 (0.46) | ALDH1A1MAPTNPSR1HSD17B10AGTR2 | |
| SCHEMBL6019299 | 0.78 | ALDH1A1 (0.46) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL28840618 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL6018931 | 0.78 | ALDH1A1 (0.46) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL6018928 | 0.78 | ALDH1A1 (0.46) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL17891866 | 0.77 | AGTR2 (0.54) | EPHX2ALDH1A1RAB9ANPC1AGTR2 | |
| SCHEMBL17891864 | 0.77 | AGTR2 (0.54) | EPHX2ALDH1A1RAB9ANPC1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024165831-A1 | IMIDAZOLIDONE AND SUCCINIMIDE DERIVATIVES FOR USE AS ALPHA V BETA 3 INTEGRIN INHIBITORS FOR THE TREATMENT OF CANCER | UNIVERSITY OF BRADFORD (GB) | 2024-08-15 | — | — | WO | disclosed |