Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RAF1 | P04049 | 5/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25594194 | 0.82 | HTT (0.34) | RAB9ARAF1MAP2K1SNCALIPE | |
| SCHEMBL5899720 | 0.79 | CA2 (0.47) | SNCAEGFRUCHL1CYP1A2CYP3A4 | |
| SCHEMBL29424578 | 0.79 | CA2 (0.47) | SNCAEGFRUCHL1CYP1A2CYP3A4 | |
| SCHEMBL25591397 | 0.79 | NPC1 (0.34) | RAB9ARAF1MAP2K1LIPENPC1 | |
| SCHEMBL22658702 | 0.79 | CA1 (0.43) | SNCA | |
| SCHEMBL30326281 | 0.78 | CSF1R (0.39) | SNCAEGFR | |
| SCHEMBL25596616 | 0.78 | MAP2K1 (0.32) | RAF1MAP2K1LIPE | |
| SCHEMBL31128931 | 0.75 | ALOX5AP (0.39) | EGFRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17200314 | 0.75 | DRD1 (0.41) | RAB9ASNCAEGFRPDGFRBPDGFRA | |
| SCHEMBL31128803 | 0.75 | RAB9A (0.44) | RAB9ARAF1MAP2K1EGFRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208315-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2024-10-10 | — | — | WO | disclosed |