Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 2/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69490 | 0.89 | JAK2 (0.55) | KMT2ANPSR1L3MBTL1MAPTTHRB | |
| SCHEMBL29114951 | 0.86 | KMT2A (0.60) | KMT2ANPSR1L3MBTL1MAPTGAA | |
| SCHEMBL69842 | 0.84 | KMT2A (0.64) | KMT2ANPSR1L3MBTL1MAPTGAA | |
| SCHEMBL30988464 | 0.84 | KMT2A (0.57) | KMT2ANPSR1L3MBTL1MAPTKDM4E | |
| SCHEMBL29452680 | 0.84 | KMT2A (0.57) | KMT2ANPSR1L3MBTL1MAPTKDM4E | |
| SCHEMBL27238319 | 0.83 | KMT2A (0.49) | KMT2ANPSR1L3MBTL1MAPTTHRB | |
| SCHEMBL1413881 | 0.81 | KMT2A (0.54) | KMT2ANPSR1L3MBTL1MAPTGAA | |
| SCHEMBL20600051 | 0.81 | KMT2A (0.54) | KMT2ANPSR1L3MBTL1THRBCYP1A2 | |
| SCHEMBL8290060 | 0.81 | SMN1; SMN2 (0.56) | KMT2ANPSR1L3MBTL1MAPTGAA | |
| SCHEMBL2314799 | 0.79 | HPGDS (0.66) | KMT2ANPSR1L3MBTL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4442318-A2 | HETEROCYCLIC INHIBITORS OF MCT4 | Vettore, LLC (US) | 2024-10-09 | — | — | EP | disclosed |