Sugi Predict

Sugi Predict / Compounds / SCHEMBL69842

SCHEMBL69842

SCHEMBL69842

CCOC(=O)c1cc(-c2ccccc2)[nH]n1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.64
▸ NPSR1 Q6W5P4 2/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.59
▸ POLB P06746 2/20 0.56
▸ TP53 P04637 1/20 0.55
▸ THRB P10828 1/20 0.55
▸ HPGDS O60760 1/20 0.54
▸ GABRA2 P47869 1/20 0.49
▸ GABRB2 P47870 1/20 0.49
▸ CYP1A2 P05177 1/20 0.49
▸ MAPT P10636 3/20 0.48
▸ LMNA P02545 3/20 0.48
▸ GAA P10253 2/20 0.48
▸ SMN1; SMN2 Q16637 2/20 0.48
▸ KDM4E B2RXH2 2/20 0.48
▸ NPC1 O15118 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ RAB9A P51151 1/20 0.48
▸ MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11887698 0.88 KMT2A (0.60) KMT2ANPSR1L3MBTL1POLBTP53
SCHEMBL29114951 0.87 KMT2A (0.60) KMT2ANPSR1L3MBTL1POLBTP53
SCHEMBL3447873 0.87 KMT2A (0.49) KMT2ANPSR1L3MBTL1POLBTP53
SCHEMBL71634 0.87 KMT2A (0.59) KMT2ANPSR1L3MBTL1POLBTP53
SCHEMBL5016810 0.86 NPSR1 (0.63) KMT2ANPSR1L3MBTL1POLBGABRA2
SCHEMBL30988463 0.86 KMT2A (0.57) KMT2ANPSR1L3MBTL1POLBTP53
SCHEMBL3501972 0.86 KMT2A (0.57) KMT2ANPSR1L3MBTL1POLBTP53
SCHEMBL70249 0.85 GABRA1 (0.54) KMT2ANPSR1L3MBTL1POLBTP53
SCHEMBL30988464 0.85 KMT2A (0.57) KMT2ANPSR1L3MBTL1POLBTP53
SCHEMBL2818771 0.85 KMT2A (0.57) KMT2ANPSR1L3MBTL1POLBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948614-A2 GLUCOKINASE ACTIVATORS Takeda San Diego, Inc. (US) 2008-07-30 — — EP claimed
US-20070197532-A1 GLUCOKINASE ACTIVATORS TAKEDA SAN DIEGO, INC. 2007-08-23 — — US claimed
WO-2007061923-A2 GLUCOKINASE ACTIVATORS TAKEDA SAN DIEGO, INC. (US) 2007-05-31 — — WO claimed
US-20260085073-A1 PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY HOTSPOT THERAPEUTICS INC (US) 2026-03-26 — — US disclosed
CN-118638119-B Pyrazole purine herbicide safener as well as preparation method and application thereof 东北农业大学 2025-02-28 — — CN disclosed
CN-118638119-A Pyrazole purine herbicide safener as well as preparation method and application thereof 东北农业大学 2024-09-13 — — CN disclosed
CN-118324752-A Five-membered heterocyclic compound with phenyl substitution, and preparation and application thereof 江西中医药大学 2024-07-12 — — CN disclosed
US-20230406830-A1 [6,6] FUSED BICYCLIC HDAC8 INHIBITORS Valo Health, LLC 2023-12-21 — — US disclosed
CN-117143019-A As beta 2 Pyrazole amide derivatives of allosteric antagonists of the adrenergic receptors 常州大学 2023-12-01 — — CN disclosed
US-11447470-B2 Pyrimidinone-containing compound, preparation method thereof, pharmaceutical composition and application thereof YUNNAN UNIVERSITY (CN) 2022-09-20 — — US disclosed
CN-109232426-B N-hydroxy-5-substituted-1H-pyrazole-3-carboxamide compound and preparation method and application thereof 中国药科大学 2022-09-16 — — CN disclosed
US-20090118335-A1 Acid Secretion Inhibitor TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-05-07 — — US disclosed
US-20090118335-A1 Acid Secretion Inhibitor TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-05-07 — — US disclosed
EP-2005957-A1 ACID SECRETION INHIBITOR Takeda Pharmaceutical Company Limited (JP) 2008-12-24 — — EP disclosed
EP-2005957-A1 ACID SECRETION INHIBITOR Takeda Pharmaceutical Company Limited (JP) 2008-12-24 — — EP disclosed
EP-1948614-A2 GLUCOKINASE ACTIVATORS Takeda San Diego, Inc. (US) 2008-07-30 — — EP disclosed
US-20070197532-A1 GLUCOKINASE ACTIVATORS TAKEDA SAN DIEGO, INC. 2007-08-23 — — US disclosed
US-20070197532-A1 GLUCOKINASE ACTIVATORS TAKEDA SAN DIEGO, INC. 2007-08-23 — — US disclosed
US-20070197532-A1 GLUCOKINASE ACTIVATORS TAKEDA SAN DIEGO, INC. 2007-08-23 — — US disclosed
WO-2007061923-A2 GLUCOKINASE ACTIVATORS TAKEDA SAN DIEGO, INC. (US) 2007-05-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11447470-B2 Pyrimidinone-containing compound, preparation method thereof, pharmaceutical composition and application thereof TYMP, DPYD, DHPS KMT2A 3182/4885NPSR1 3356/4885L3MBTL1 4729/4885
US-20090118335-A1 Acid Secretion Inhibitor ATP6AP1, HRH2, ATP6V1G1 KMT2A 4237/4885NPSR1 1002/4885L3MBTL1 4005/4885
US-20230406830-A1 [6,6] FUSED BICYCLIC HDAC8 INHIBITORS HDAC8, HDAC3, HDAC2 KMT2A 48/4885NPSR1 1701/4885L3MBTL1 782/4885
US-20070197532-A1 GLUCOKINASE ACTIVATORS GCK, GCKR, GALK1 KMT2A 3325/4885NPSR1 4410/4885L3MBTL1 4625/4885
US-20260085073-A1 PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY MALT1, BCL6, BCL3 KMT2A 2239/4885NPSR1 4146/4885L3MBTL1 1074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.