Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24932119 | 0.90 | ALDH1A1 (0.49) | IDO1CARM1PRMT6TEKFFAR2 | |
| SCHEMBL27211133 | 0.87 | IDO1 (0.41) | IDO1FFAR2MAPTALDH1A1TDP1 | |
| SCHEMBL24298066 | 0.86 | FFAR2 (0.45) | FFAR2ALDH1A1LMNACDK8RAB9A | |
| SCHEMBL31132482 | 0.86 | CARM1 (0.43) | IDO1CARM1PRMT6FFAR2TP53 | |
| SCHEMBL27210967 | 0.84 | ALDH1A1 (0.40) | IDO1FFAR2MAPTALDH1A1TDP1 | |
| SCHEMBL31132625 | 0.84 | NPC1 (0.53) | FFAR2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL27211481 | 0.83 | FFAR2 (0.39) | IDO1TEKFFAR2MAPTALDH1A1 | |
| SCHEMBL29564448 | 0.83 | CYP3A4 (0.53) | — | |
| SCHEMBL27211265 | 0.83 | CYP3A4 (0.53) | — | |
| SCHEMBL24931470 | 0.83 | ABL1 (0.44) | CARM1PRMT6TEKSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704830-A2 | MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF | Septerna, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226914-A2 | MRGPRX2 ANTAGONISTS AND METHODS OF USE THEREOF | SEPTERNA, INC. (US) | 2024-10-31 | — | — | WO | disclosed |