Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KDM5C | P41229 | 2/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12682404 | 1.00 | ATR (0.47) | ATRKDM4CKDM4EKDM5CKDM6B | |
| SCHEMBL27426145 | 0.93 | ACACB (0.43) | ATRKDM4CKDM4EKDM5CKDM6B | |
| SCHEMBL509487 | 0.89 | KDM5B (0.53) | KDM4CKDM4EKDM5CALOX15ACACB | |
| SCHEMBL30097021 | 0.88 | ACACB (0.46) | ATRKDM4CKDM4EKDM5CKDM6B | |
| SCHEMBL508770 | 0.88 | ACACB (0.46) | ATRKDM4CKDM4EKDM5CKDM6B | |
| SCHEMBL3416327 | 0.87 | ACACB (0.45) | ATRKDM4CKDM4EKDM5CKDM6B | |
| SCHEMBL10285171 | 0.87 | KDM5A (0.46) | ATRKDM4CKDM4EKDM5CL3MBTL1 | |
| SCHEMBL3312747 | 0.87 | HDAC1 (0.44) | ATRKDM4EACACBACACANAMPT | |
| SCHEMBL23705885 | 0.84 | P4HB (0.42) | ATRKDM4CKDM4EKDM5CKDM6B | |
| SCHEMBL30097022 | 0.84 | P4HB (0.42) | ATRKDM4CKDM4EKDM5CKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704830-A2 | MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF | Septerna, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226914-A2 | MRGPRX2 ANTAGONISTS AND METHODS OF USE THEREOF | SEPTERNA, INC. (US) | 2024-10-31 | — | — | WO | disclosed |