Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 5/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23705885 | 1.00 | P4HB (0.42) | P4HBATRACACBACACABRD4 | |
| SCHEMBL23706002 | 0.87 | KDM4A (0.44) | ACACBACACABRD4KDM4EALDH1A1 | |
| SCHEMBL12682404 | 0.84 | ATR (0.47) | ATRACACBACACABRD4KDM4E | |
| SCHEMBL31133034 | 0.84 | ATR (0.47) | ATRACACBACACABRD4KDM4E | |
| SCHEMBL3416327 | 0.84 | ACACB (0.45) | ATRACACBACACABRD4KDM4E | |
| SCHEMBL30096997 | 0.81 | ACACB (0.40) | ATRACACBACACABRD4KDM4E | |
| SCHEMBL23705963 | 0.81 | ACACB (0.40) | ATRACACBACACABRD4KDM4E | |
| SCHEMBL29792768 | 0.80 | KDM4A (0.39) | ATRACACBACACABRD4KDM4E | |
| SCHEMBL23705888 | 0.80 | LOXL2 (0.51) | P4HBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30992907 | 0.79 | P4HB (0.48) | P4HBGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |