Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 5/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992405 | 1.00 | L3MBTL1 (0.59) | L3MBTL1POLBMAPK1ASPHSIRT6 | |
| SCHEMBL16466573 | 0.88 | SIRT6 (0.57) | L3MBTL1POLBMAPK1SIRT6MAPT | |
| SCHEMBL16293478 | 0.87 | L3MBTL1 (0.45) | L3MBTL1MAPK1ASPHSIRT6MAPT | |
| SCHEMBL16935146 | 0.85 | L3MBTL1 (0.50) | L3MBTL1POLBMAPK1SIRT6MAPT | |
| SCHEMBL16293371 | 0.84 | L3MBTL1 (0.43) | L3MBTL1POLBMAPK1ASPHSIRT6 | |
| SCHEMBL841915 | 0.83 | EPHX2 (0.46) | L3MBTL1ASPHSIRT6EPHX2BACE1 | |
| SCHEMBL31132803 | 0.82 | L3MBTL1 (0.48) | L3MBTL1MAPK1SIRT6MAPTBACE1 | |
| SCHEMBL2108636 | 0.82 | L3MBTL1 (0.48) | L3MBTL1MAPK1SIRT6MAPTBACE1 | |
| SCHEMBL24214121 | 0.82 | L3MBTL1 (0.41) | L3MBTL1ASPHSIRT6EPHX2BACE1 | |
| SCHEMBL14903884 | 0.81 | L3MBTL1 (0.47) | L3MBTL1BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704830-A2 | MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF | Septerna, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226914-A2 | MRGPRX2 ANTAGONISTS AND METHODS OF USE THEREOF | SEPTERNA, INC. (US) | 2024-10-31 | — | — | WO | disclosed |