Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21818652 | 1.00 | P2RX7 (0.58) | P2RX7MGLLALDH1A1MTHFD2SHMT2 | |
| SCHEMBL21893742 | 0.89 | MGLL (0.58) | P2RX7MGLL | |
| SCHEMBL21818611 | 0.85 | P2RX7 (0.73) | P2RX7ALDH1A1MTHFD2 | |
| SCHEMBL31133303 | 0.85 | P2RX7 (0.73) | P2RX7ALDH1A1MTHFD2 | |
| SCHEMBL23872228 | 0.83 | P2RX7 (0.47) | P2RX7MGLLALDH1A1PDE2A | |
| SCHEMBL21819399 | 0.83 | P2RX7 (0.64) | P2RX7MGLLMTHFD2 | |
| SCHEMBL31133378 | 0.83 | P2RX7 (0.64) | P2RX7MGLLMTHFD2 | |
| SCHEMBL31133399 | 0.82 | P2RX7 (0.61) | P2RX7MGLLALDH1A1SHMT2 | |
| SCHEMBL21819467 | 0.82 | P2RX7 (0.61) | P2RX7MGLLALDH1A1SHMT2 | |
| SCHEMBL21819229 | 0.80 | P2RX7 (0.63) | P2RX7MTHFD2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164459-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-03 | — | — | CN | disclosed |