Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | VNN1 | O95497 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | USP9X | Q93008 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16044509 | 1.00 | MGAM (0.42) | MGAMGPR183ALDH1A1MAPK1POLB | |
| SCHEMBL104460 | 0.84 | KDM4E (0.50) | GPR183ALDH1A1POLBVNN1TSHR | |
| SCHEMBL25787974 | 0.84 | TSHR (0.54) | GPR183POLBVNN1TSHRMAPT | |
| SCHEMBL14645431 | 0.80 | NPC1 (0.40) | GPR183POLBVNN1TSHRPKM | |
| SCHEMBL19020851 | 0.79 | MGAM (0.51) | MGAMALDH1A1MAPK1POLBVNN1 | |
| SCHEMBL29618351 | 0.77 | ALDH1A1 (0.40) | MGAMALDH1A1MAPK1POLBVNN1 | |
| SCHEMBL10650921 | 0.77 | MGAM (0.41) | MGAMALDH1A1POLBKDM4EP4HA1 | |
| SCHEMBL30133833 | 0.76 | MGAM (0.37) | MGAMALDH1A1MAPK1POLBKDM4E | |
| SCHEMBL17996637 | 0.76 | NTRK1 (0.41) | GPR183ALDH1A1POLBVNN1TSHR | |
| SCHEMBL21816424 | 0.75 | MGLL (0.40) | MGAMALDH1A1MAPK1POLBVNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164459-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-03 | — | — | CN | disclosed |