Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 3/20 | 0.47 |
| ▸ | DGKZ | Q13574 | 3/20 | 0.47 |
| ▸ | SCD | O00767 | 3/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526862 | 1.00 | DGKA (0.47) | DGKADGKZSCDNR3C1CHRM4 | |
| SCHEMBL31133650 | 0.93 | DGKA (0.46) | DGKADGKZSCDCHRM4HRH3 | |
| SCHEMBL31133750 | 0.93 | DGKA (0.52) | DGKADGKZSCDCHRM4MCHR1 | |
| SCHEMBL23527307 | 0.93 | DGKA (0.46) | DGKADGKZSCDCHRM4HRH3 | |
| SCHEMBL23527176 | 0.93 | DGKA (0.52) | DGKADGKZSCDCHRM4MCHR1 | |
| SCHEMBL23527095 | 0.92 | HRH3 (0.47) | DGKADGKZGPR6HRH3 | |
| SCHEMBL31133498 | 0.92 | HRH3 (0.47) | DGKADGKZGPR6HRH3 | |
| SCHEMBL23527004 | 0.92 | DGKA (0.46) | DGKADGKZSCDCHRM4HRH3 | |
| SCHEMBL31133736 | 0.92 | DGKA (0.46) | DGKADGKZSCDCHRM4HRH3 | |
| SCHEMBL23527014 | 0.91 | DGKA (0.44) | DGKADGKZSCDCHRM4GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081523-B1 | SUBSTITUTED BICYCLIC PIPERIDINE DERIVATIVES USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2024-12-25 | — | — | EP | claimed |
| CN-114901660-B | Substituted bicyclic compounds useful as T cell activators | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | claimed |
| CN-114901660-B | Substituted bicyclic compounds useful as T cell activators | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | disclosed |