Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16355875 | 1.00 | MTNR1A (0.45) | MTNR1AMTNR1BCYP4F2CYP4A11LMNA | |
| SCHEMBL14860053 | 0.88 | MTNR1A (0.45) | MTNR1AMTNR1BCYP4F2CYP4A11LMNA | |
| SCHEMBL30394978 | 0.87 | MTNR1A (0.46) | MTNR1AMTNR1BCYP4F2CYP4A11LMNA | |
| SCHEMBL31119031 | 0.84 | HPGD (0.54) | CYP4F2CYP4A11LMNAHPGDMRGPRX4 | |
| SCHEMBL1287529 | 0.84 | HPGD (0.54) | CYP4F2CYP4A11LMNAHPGDMRGPRX4 | |
| SCHEMBL1179585 | 0.82 | CYP4F2 (0.49) | CYP4F2CYP4A11HPGDALDH1A1KDM4E | |
| SCHEMBL7597341 | 0.81 | MRGPRX4 (0.57) | CYP4F2CYP4A11HPGDMRGPRX4ALDH1A1 | |
| SCHEMBL4052165 | 0.81 | CYP4F2 (0.67) | CYP4F2CYP4A11LMNAALDH1A1HTT | |
| SCHEMBL16355870 | 0.81 | CYP4F2 (0.44) | CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL3528211 | 0.80 | ALDH1A1 (0.50) | LMNAHPGDALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451058-A | RXFP1 agonists | 百时美施贵宝公司 | 2024-08-06 | — | — | CN | disclosed |