Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615057 | 1.00 | MAP2K1 (0.36) | MAP2K1HPGDALDH1A1KDM4EGAA | |
| SCHEMBL16855028 | 0.88 | HPGD (0.42) | MAP2K1HPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL24195828 | 0.87 | CSF1R (0.39) | MAP2K1HPGDALDH1A1KDM4EGAA | |
| SCHEMBL31135631 | 0.86 | MAP2K1 (0.50) | MAP2K1 | |
| SCHEMBL23850846 | 0.86 | MAP2K1 (0.50) | MAP2K1 | |
| SCHEMBL1615794 | 0.85 | MAP2K1 (0.38) | MAP2K1HPGDALDH1A1KDM4EGAA | |
| SCHEMBL31135605 | 0.85 | MAP2K1 (0.38) | MAP2K1HPGDALDH1A1KDM4EGAA | |
| SCHEMBL24196144 | 0.84 | MAP2K1 (0.35) | MAP2K1HPGDALDH1A1KDM4EGAA | |
| SCHEMBL1615894 | 0.83 | KEAP1 (0.37) | MAP2K1KDM4EDHODHPIK3CG | |
| SCHEMBL31135656 | 0.83 | KEAP1 (0.37) | MAP2K1KDM4EDHODHPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113645964-B | Arylaniline and heteroaryl aniline compounds for fetal treatment | 恩福莱克逊治疗有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-113660931-B | Arylaniline and heteroaryl aniline compounds for the treatment of skin cancer | 恩福莱克逊治疗有限公司 | 2024-10-11 | — | — | CN | disclosed |