⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851073 | 0.92 | CA2 (0.54) | — | |
| SCHEMBL14892732 | 0.90 | CA2 (0.58) | — | |
| Alcohol SCHEMBL8778843 | 0.86 | CA2 (0.46) | — | |
| SCHEMBL552729 | 0.85 | — | — | |
| Propanol SCHEMBL8778756 | 0.83 | ALDH1A1 (0.45) | — | |
| SCHEMBL3103133 | 0.82 | — | — | |
| Fluoride SCHEMBL28014213 | 0.82 | CA2 (0.48) | — | |
| SCHEMBL52570 | 0.82 | CA2 (0.52) | — | |
| SCHEMBL2823957 | 0.82 | — | — | |
| SCHEMBL3105101 | 0.81 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160200734-A1 | CARBOXYLIC ACID COMPOUNDS IN TREATMENT OF DIABETES MELLITUS | KANG, XINSHAN (CN) | 2016-07-14 | — | — | US | disclosed |
| EP-3036237-A1 | CARBOXYLIC ACID COMPOUNDS IN TREATMENT OF DIABETES MELLITUS | Fujian Haixi Pharmaceuticals Co. Ltd (CN) | 2016-06-29 | — | — | EP | disclosed |
| US-9187450-B2 | Substituted pyridine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-11-17 | — | — | US | disclosed |
| EP-2592076-B1 | SUBSTITUTED PYRIDINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2015-05-13 | — | — | EP | disclosed |
| WO-2015024526-A1 | CARBOXYLIC ACID COMPOUNDS IN TREATMENT OF DIABETES MELLITUS | FUJIAN HAIXI PHARMACEUTICALS CO., LTD (CN) | 2015-02-26 | — | — | WO | disclosed |
| US-20140213549-A9 | Substituted Pyridine Compound | UBE INDUSTRIES, LTD. (JP) | 2014-07-31 | — | — | US | disclosed |
| US-20140005143-A2 | Substituted PyridineCompound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-01-02 | — | — | US | disclosed |
| EP-2592076-A1 | SUBSTITUTED PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-05-15 | — | — | EP | disclosed |
| US-20130109653-A1 | Substituted Pyridine Compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-02 | — | — | US | disclosed |
| US-8222417-B2 | Compound having 11β-HSD1 inhibitory activity | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100179325-A1 | COMPOUND HAVING 11BETA-HSD1 INHIBITORY ACTIVITY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-07-15 | — | — | US | disclosed |
| EP-2172453-A1 | COMPOUND HAVING 11 ß-HSD1 INHIBITORY ACTIVITY | Taisho Pharmaceutical Co. Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
| US-4057418-A | Sulfonylmethylamino-substituted benzoic acids and herbicidal method therewith | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-08 | — | — | US | disclosed |