Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113775 | 1.00 | GFER (0.37) | GFERTRIM24TRIM33HDAC6MMP2 | |
| SCHEMBL2793358 | 0.85 | GFER (0.41) | GFERHDAC6MMP2CES2KMT2A | |
| SCHEMBL2793360 | 0.85 | GFER (0.41) | GFERHDAC6MMP2CES2KMT2A | |
| SCHEMBL3112950 | 0.84 | GFER (0.35) | GFERHDAC6CES2KMT2AALDH1A1 | |
| SCHEMBL12540135 | 0.84 | GFER (0.35) | GFERHDAC6CES2KMT2AALDH1A1 | |
| SCHEMBL3112948 | 0.84 | GFER (0.35) | GFERHDAC6CES2KMT2AALDH1A1 | |
| SCHEMBL3113702 | 0.81 | GFER (0.41) | GFERHDAC6MMP2CES2KMT2A | |
| SCHEMBL4234097 | 0.81 | GFER (0.41) | GFERHDAC6MMP2CES2KMT2A | |
| SCHEMBL3123001 | 0.80 | GFER (0.39) | GFERHDAC6MMP2CES2KMT2A | |
| SCHEMBL3123005 | 0.80 | GFER (0.39) | GFERHDAC6MMP2CES2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971581-B1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2010-04-07 | — | — | EP | disclosed |