Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4234097 | 1.00 | GFER (0.41) | GFERCAPN1HDAC6CES2PLA2G10 | |
| SCHEMBL3119435 | 0.87 | GFER (0.37) | GFERCAPN1HDAC6CES2PLA2G10 | |
| SCHEMBL3119429 | 0.87 | GFER (0.37) | GFERCAPN1HDAC6CES2PLA2G10 | |
| SCHEMBL2793358 | 0.85 | GFER (0.41) | GFERCAPN1HDAC6CES2PLA2G10 | |
| SCHEMBL2793360 | 0.85 | GFER (0.41) | GFERCAPN1HDAC6CES2PLA2G10 | |
| SCHEMBL3115362 | 0.83 | MAPT (0.43) | HDAC6LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2794403 | 0.82 | GFER (0.39) | GFERCAPN1HDAC6CES2PLA2G10 | |
| SCHEMBL2794405 | 0.82 | GFER (0.39) | GFERCAPN1HDAC6CES2PLA2G10 | |
| SCHEMBL3017361 | 0.81 | XDH (0.50) | GFERNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL3017358 | 0.81 | XDH (0.50) | GFERNPSR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971581-B1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2010-04-07 | — | — | EP | disclosed |
| US-20090137396-A1 | Piperazine Compounds with a Herbicidal Action | BASF SE (DE) | 2009-05-28 | — | — | US | disclosed |
| EP-1971581-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2008-09-24 | — | — | EP | disclosed |
| EP-1968991-A1 | BIS-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY | Sede Secondaria Della Cell Therapeutics, Inc. (IT) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007077247-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007071415-A1 | BIS-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY | CELL THERAPEUTICS, INC. - SEDE SECONDARIA (IT) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137396-A1 | Piperazine Compounds with a Herbicidal Action | DDT, CIP2A, PFAS | GFER 1334/4885CAPN1 511/4885HDAC6 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.