Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112950 | 1.00 | GFER (0.35) | GFERRIPK1CES2HDAC6KMT2A | |
| SCHEMBL12540135 | 1.00 | GFER (0.35) | GFERRIPK1CES2HDAC6KMT2A | |
| SCHEMBL3113775 | 0.84 | GFER (0.37) | GFERCES2HDAC6KMT2AALDH1A1 | |
| SCHEMBL3113774 | 0.84 | GFER (0.37) | GFERCES2HDAC6KMT2AALDH1A1 | |
| SCHEMBL2794403 | 0.84 | GFER (0.39) | GFERRIPK1CES2HDAC6KMT2A | |
| SCHEMBL2794405 | 0.84 | GFER (0.39) | GFERRIPK1CES2HDAC6KMT2A | |
| SCHEMBL3112682 | 0.82 | GFER (0.38) | GFERCES2HDAC6KMT2ACAPN1 | |
| SCHEMBL3112688 | 0.82 | GFER (0.38) | GFERCES2HDAC6KMT2ACAPN1 | |
| SCHEMBL3113702 | 0.78 | GFER (0.41) | GFERCES2HDAC6KMT2AALDH1A1 | |
| SCHEMBL2793358 | 0.78 | GFER (0.41) | GFERCES2HDAC6KMT2ACAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971581-B1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2010-04-07 | — | — | EP | disclosed |