Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352445 | 0.83 | L3MBTL1 (0.44) | LMNAPOLBCYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL10817963 | 0.75 | CYP2A6 (0.62) | LMNACYP2A6CYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL3572760 | 0.73 | HSP90AA1 (0.57) | LMNAPOLBCYP2A6CYP1A2CYP3A4 | |
| SCHEMBL27877200 | 0.71 | CYP2A6 (0.62) | LMNAPOLBCYP2A6CYP1A2SMN1; SMN2 | |
| SCHEMBL29933915 | 0.71 | CYP2A6 (0.62) | LMNAPOLBCYP2A6CYP1A2SMN1; SMN2 | |
| SCHEMBL15966607 | 0.71 | CYP2A6 (0.62) | LMNAPOLBCYP2A6CYP1A2SMN1; SMN2 | |
| SCHEMBL15972704 | 0.71 | CYP2A6 (0.62) | LMNACYP2A6CYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL4631413 | 0.71 | CYP2A6 (0.62) | LMNAPOLBCYP2A6CYP1A2SMN1; SMN2 | |
| SCHEMBL18905348 | 0.71 | CYP2A6 (0.62) | LMNACYP2A6CYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL16320822 | 0.71 | CYP2A6 (0.62) | LMNACYP2A6CYP1A2SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4685141-A1 | ISOINDOLINE DERIVATIVE, BENZOINDOLE DERIVATIVE AND USE THEREOF | Shanghai Helioson Pharmaceutical Co., Ltd. (CN) | 2026-01-28 | — | — | EP | disclosed |
| WO-2024193641-A1 | ISOINDOLINE DERIVATIVE, BENZOINDOLE DERIVATIVE AND USE THEREOF | 上海超阳药业有限公司 | 2024-09-26 | — | — | WO | disclosed |