Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138255 | 0.83 | LMNA (0.63) | LMNAPOLBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27492088 | 0.82 | NPC1 (0.42) | L3MBTL1POLBITKMAPTALDH1A1 | |
| SCHEMBL28545192 | 0.81 | ATM (0.39) | L3MBTL1LMNAPOLBCYP1A2CYP3A4 | |
| SCHEMBL5700203 | 0.73 | PLAU (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19PTGS2 | |
| SCHEMBL18002784 | 0.71 | CYP1A2 (0.39) | L3MBTL1POLBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9120149 | 0.71 | MAPK8 (0.44) | LMNACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5426681 | 0.71 | COMT (0.43) | L3MBTL1LMNAPOLBNPSR1ITK | |
| SCHEMBL832407 | 0.71 | L3MBTL1 (0.50) | L3MBTL1LMNAPOLBCYP1A2CYP2C9 | |
| SCHEMBL3599059 | 0.71 | LOX (0.35) | LMNAPOLBALOX15 | |
| SCHEMBL32526767 | 0.71 | L3MBTL1 (0.50) | L3MBTL1LMNAPOLBCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007129169-A2 | COX- II INHIBITORS FOR IMPROVING REPRODUCTIVE SUCCESS IN A FEMALE ANIMAL | PFIZER LIMITED (GB) | 2007-11-15 | — | — | WO | disclosed |