Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 14/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138488 | 0.84 | USP1 (0.33) | USP1MMP13 | |
| SCHEMBL31138559 | 0.82 | HDAC1 (0.33) | USP1MMP13 | |
| SCHEMBL31138428 | 0.79 | USP1 (0.37) | USP1 | |
| SCHEMBL31138511 | 0.79 | USP1 (0.32) | USP1MMP13 | |
| SCHEMBL31138586 | 0.78 | USP1 (0.49) | USP1 | |
| SCHEMBL31138572 | 0.77 | USP1 (0.34) | USP1 | |
| SCHEMBL31138563 | 0.74 | USP1 (0.34) | USP1 | |
| SCHEMBL31138614 | 0.73 | USP1 (0.35) | USP1 | |
| SCHEMBL31254924 | 0.73 | USP1 (0.37) | USP1 | |
| SCHEMBL31138518 | 0.71 | USP1 (0.38) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233605-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |