Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 9/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138509 | 0.88 | USP1 (0.33) | USP1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL31138428 | 0.86 | USP1 (0.37) | USP1HDAC1HDAC6HDAC5 | |
| SCHEMBL31138577 | 0.81 | USP1 (0.44) | USP1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL31138488 | 0.80 | USP1 (0.33) | USP1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL31138404 | 0.79 | HTR2C (0.35) | USP1MMP13 | |
| SCHEMBL31138559 | 0.79 | HDAC1 (0.33) | USP1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL31138394 | 0.77 | HDAC1 (0.38) | USP1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL31138747 | 0.76 | USP1 (0.34) | USP1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL31254924 | 0.74 | USP1 (0.37) | USP1 | |
| SCHEMBL31138518 | 0.72 | USP1 (0.38) | USP1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233605-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |