SCHEMBL31138531

SCHEMBL31138531

COc1ncnc(C2CC2)c1-c1nc(OCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)c2c(ncn2CCS(C)(=O)=O)n1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.58
▸ WDR48 Q8TAF3 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31138693 0.94 USP1 (0.59) USP1WDR48
SCHEMBL31138780 0.90 USP1 (0.61) USP1WDR48
SCHEMBL31138778 0.90 USP1 (0.61) USP1WDR48
SCHEMBL31138736 0.90 USP1 (0.60) USP1WDR48
SCHEMBL31138556 0.89 USP1 (0.62) USP1WDR48
SCHEMBL31138530 0.89 USP1 (0.60) USP1WDR48
SCHEMBL31138481 0.89 USP1 (0.62) USP1WDR48
SCHEMBL31138671 0.89 USP1 (0.60) USP1WDR48
SCHEMBL31138632 0.86 USP1 (0.58) USP1WDR48
SCHEMBL31138564 0.85 USP1 (0.60) USP1WDR48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233605-A1 COMPOUNDS AND THEIR USE AGAINST CANCER TANGO THERAPEUTICS, INC. (US) 2024-11-14 — — WO disclosed
Send feedback