Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138559 | 0.86 | HDAC1 (0.33) | USP1HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL31155899 | 0.85 | USP1 (0.41) | USP1HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL31138614 | 0.84 | USP1 (0.35) | USP1HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL31138563 | 0.83 | USP1 (0.34) | USP1HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL31138675 | 0.82 | USP1 (0.33) | USP1HDAC6HDAC1HDAC5 | |
| SCHEMBL31138496 | 0.82 | USP1 (0.33) | USP1 | |
| SCHEMBL31138764 | 0.80 | USP1 (0.42) | USP1 | |
| SCHEMBL31254619 | 0.80 | USP1 (0.37) | USP1HDAC6HDAC1HDAC5 | |
| SCHEMBL31138509 | 0.79 | USP1 (0.33) | USP1HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL31138630 | 0.74 | USP1 (0.34) | USP1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233605-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |