Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 19/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138552 | 0.85 | USP1 (0.33) | USP1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL31138403 | 0.85 | USP1 (0.42) | USP1 | |
| SCHEMBL31155858 | 0.83 | USP1 (0.42) | USP1 | |
| SCHEMBL31138542 | 0.80 | USP1 (0.41) | USP1HDAC1HDAC8HDAC6 | |
| SCHEMBL31254974 | 0.79 | USP1 (0.43) | USP1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL31155874 | 0.78 | USP1 (0.49) | USP1 | |
| SCHEMBL31138445 | 0.78 | USP1 (0.42) | USP1 | |
| SCHEMBL31155889 | 0.75 | USP1 (0.46) | USP1 | |
| SCHEMBL31254997 | 0.75 | USP1 (0.48) | USP1 | |
| SCHEMBL31254882 | 0.73 | USP1 (0.45) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208292-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITOR, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2024-10-10 | — | — | WO | disclosed |