Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.42 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138495 | 0.89 | DGAT1 (0.48) | DGAT1USP1 | |
| SCHEMBL31138694 | 0.89 | DGAT1 (0.43) | DGAT1USP1HDAC1HDAC6HDAC5 | |
| SCHEMBL31138420 | 0.88 | DGAT1 (0.42) | DGAT1USP1HDAC1HDAC6HDAC5 | |
| SCHEMBL31138410 | 0.87 | DGAT1 (0.41) | DGAT1USP1HDAC1HDAC6HDAC5 | |
| SCHEMBL31138656 | 0.82 | USP1 (0.56) | USP1 | |
| SCHEMBL31138385 | 0.78 | DGAT1 (0.44) | DGAT1USP1HDAC1HDAC6HDAC5 | |
| SCHEMBL31138602 | 0.78 | DGAT1 (0.43) | DGAT1USP1 | |
| SCHEMBL31138471 | 0.77 | DGAT1 (0.48) | DGAT1USP1 | |
| SCHEMBL31138399 | 0.77 | DGAT1 (0.48) | DGAT1USP1 | |
| SCHEMBL31138654 | 0.76 | DGAT1 (0.45) | DGAT1USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233605-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |