SCHEMBL31138576

SCHEMBL31138576

CC(C)c1ccccc1-c1nc(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)c2[nH]c(=O)ccc2n1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.56
▸ WDR48 Q8TAF3 14/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31557982 0.83 USP1 (0.70) USP1WDR48
SCHEMBL31423509 0.82 USP1 (0.62) USP1WDR48
SCHEMBL31423526 0.82 PIP4K2C (0.57) USP1WDR48
SCHEMBL31138756 0.81 USP1 (0.51) USP1WDR48
SCHEMBL31625208 0.80 USP1 (0.53) USP1WDR48
SCHEMBL31423609 0.80 USP1 (0.62) USP1WDR48
SCHEMBL31623596 0.80 USP1 (0.52) USP1WDR48
SCHEMBL31624993 0.80 USP1 (0.63) USP1WDR48
SCHEMBL18865831 0.79 USP1 (0.68) USP1WDR48
SCHEMBL31423524 0.79 USP1 (0.64) USP1WDR48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233605-A1 COMPOUNDS AND THEIR USE AGAINST CANCER TANGO THERAPEUTICS, INC. (US) 2024-11-14 — — WO disclosed
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