SCHEMBL31138672

SCHEMBL31138672

COc1nc(-c2nc(C(F)(F)F)cn2C2CC2)ccc1COc1nc(-c2c(OC)ncnc2C2CC2)nc2ncccc12

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.49
▸ WDR48 Q8TAF3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31138406 0.87 USP1 (0.49) USP1WDR48
SCHEMBL31138444 0.84 USP1 (0.35) USP1
SCHEMBL31537625 0.81 USP1 (0.55) USP1WDR48
SCHEMBL31138689 0.81 USP1 (0.51) USP1WDR48
SCHEMBL31537686 0.80 USP1 (0.62) USP1WDR48
SCHEMBL31537642 0.80 USP1 (0.61) USP1WDR48
SCHEMBL31138636 0.79 USP1 (0.42) USP1WDR48
SCHEMBL31138553 0.79 USP1 (0.55) USP1WDR48
SCHEMBL31138409 0.77 USP1 (0.64) USP1WDR48
SCHEMBL31537652 0.77 USP1 (0.55) USP1WDR48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233605-A1 COMPOUNDS AND THEIR USE AGAINST CANCER TANGO THERAPEUTICS, INC. (US) 2024-11-14 — — WO disclosed
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