SCHEMBL31138689

SCHEMBL31138689

FC(F)Oc1ncnc(C2CC2)c1-c1nc(OCc2ccc(-c3nc(C(F)(F)F)cn3C3CC3)cc2)c2cccnc2n1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.51
▸ WDR48 Q8TAF3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31138636 0.89 USP1 (0.42) USP1WDR48
SCHEMBL31254639 0.84 USP1 (0.56) USP1WDR48
SCHEMBL31254554 0.83 USP1 (0.62) USP1WDR48
SCHEMBL31537686 0.83 USP1 (0.62) USP1WDR48
SCHEMBL31254847 0.82 USP1 (0.52) USP1WDR48
SCHEMBL31537618 0.81 USP1 (0.55) USP1WDR48
SCHEMBL31255068 0.81 USP1 (0.51) USP1WDR48
SCHEMBL31138672 0.81 USP1 (0.49) USP1WDR48
SCHEMBL31138628 0.80 USP1 (0.60) USP1WDR48
SCHEMBL31138542 0.79 USP1 (0.41) USP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233605-A1 COMPOUNDS AND THEIR USE AGAINST CANCER TANGO THERAPEUTICS, INC. (US) 2024-11-14 — — WO disclosed
Send feedback