Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.58 |
| ▸ | BCHE | P06276 | 8/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265843 | 0.97 | ACHE (0.61) | ACHEBCHECHRM1EPHX2GRIN1 | |
| SCHEMBL4276722 | 0.92 | ACHE (0.60) | ACHEBCHECHRM1EPHX2 | |
| SCHEMBL4271348 | 0.91 | ACHE (0.59) | ACHEBCHECHRM1EPHX2 | |
| SCHEMBL4267672 | 0.90 | BCHE (0.58) | ACHEBCHECHRM1EPHX2 | |
| SCHEMBL4268755 | 0.90 | BCHE (0.58) | ACHEBCHECHRM1EPHX2 | |
| SCHEMBL4270443 | 0.90 | BCHE (0.58) | ACHEBCHECHRM1EPHX2 | |
| SCHEMBL4280010 | 0.90 | BCHE (0.58) | ACHEBCHECHRM1EPHX2 | |
| SCHEMBL4280053 | 0.90 | BCHE (0.58) | ACHEBCHECHRM1EPHX2 | |
| SCHEMBL4274740 | 0.90 | BCHE (0.58) | ACHEBCHECHRM1EPHX2 | |
| SCHEMBL31139204 | 0.89 | ACHE (0.63) | ACHEBCHECHRM1EPHX2GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118724871-B | Pyrazolone-tacrine compound and preparation method and application thereof | 安徽中医药大学 | 2025-01-28 | — | — | CN | disclosed |
| CN-118724871-A | Pyrazolone-tacrine compound and preparation method and application thereof | 安徽中医药大学 | 2024-10-01 | — | — | CN | disclosed |