Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.58 |
| ▸ | ACHE | P22303 | 6/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4270443 | 1.00 | BCHE (0.58) | BCHEACHECHRM1EPHX2 | |
| SCHEMBL4280053 | 1.00 | BCHE (0.58) | BCHEACHECHRM1EPHX2 | |
| SCHEMBL4274740 | 1.00 | BCHE (0.58) | BCHEACHECHRM1EPHX2 | |
| SCHEMBL4268755 | 1.00 | BCHE (0.58) | BCHEACHECHRM1EPHX2 | |
| SCHEMBL4267672 | 1.00 | BCHE (0.58) | BCHEACHECHRM1EPHX2 | |
| SCHEMBL4271348 | 0.99 | ACHE (0.59) | BCHEACHECHRM1EPHX2 | |
| SCHEMBL4276722 | 0.95 | ACHE (0.60) | BCHEACHECHRM1EPHX2 | |
| SCHEMBL4265843 | 0.92 | ACHE (0.61) | BCHEACHECHRM1EPHX2 | |
| SCHEMBL31139202 | 0.90 | ACHE (0.58) | BCHEACHECHRM1EPHX2 | |
| SCHEMBL31139204 | 0.86 | ACHE (0.63) | BCHEACHECHRM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605265-B2 | Heterodimers and methods of using them | Biotechnology Research Corporation Ltd. (CN) | 2009-10-20 | — | — | US | disclosed |
| US-20080176308-A1 | Heterodimers and Methods of Using Them | BIOTECHNOLOGY RESEARCH CORPORATION LIMITED (CN) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176308-A1 | Heterodimers and Methods of Using Them | GRIN2A, GRIN3A, GRIN1 | BCHE 47/4885ACHE 93/4885CHRM1 860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.