Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 14/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660176 | 1.00 | SMYD3 (0.58) | SMYD3HDAC3PTPN1TRPV1 | |
| SCHEMBL23143565 | 0.89 | TRPV1 (0.56) | SMYD3HDAC3PTPN1TRPV1 | |
| SCHEMBL5842454 | 0.86 | TLK2 (0.57) | SMYD3HDAC3PTPN1 | |
| SCHEMBL4415749 | 0.82 | TLK2 (0.56) | SMYD3HDAC3 | |
| SCHEMBL396708 | 0.82 | KCNK3 (0.57) | SMYD3TRPV1 | |
| SCHEMBL3193164 | 0.80 | SMYD3 (0.61) | SMYD3 | |
| SCHEMBL26547572 | 0.80 | SMYD3 (0.56) | SMYD3HDAC3 | |
| SCHEMBL3195105 | 0.80 | CRBN (0.68) | SMYD3HDAC3 | |
| SCHEMBL19691220 | 0.80 | SMYD3 (0.61) | SMYD3HDAC3 | |
| SCHEMBL16048824 | 0.80 | SMYD3 (0.67) | SMYD3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3935050-B1 | HETEROCYCLIC COMPOUNDS FOR MEDICAL TREATMENT | C4 THERAPEUTICS INC (US) | 2024-10-02 | — | — | EP | disclosed |