SCHEMBL23143565

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL396708	0.92	KCNK3 (0.57)	TRPV1SMYD3CRBN
	SCHEMBL31139504	0.89	SMYD3 (0.58)	TRPV1SMYD3HDAC3PTPN1
	SCHEMBL3660176	0.89	SMYD3 (0.58)	TRPV1SMYD3HDAC3PTPN1
	SCHEMBL24124323	0.89	TRPV1 (0.50)	TRPV1SMYD3CRBNHDAC1HDAC3
	SCHEMBL25921128	0.88	GPR27 (0.60)	TRPV1NPC1PKMRAB9ASMN1; SMN2
	SCHEMBL23143516	0.86	BACE1 (0.56)	TRPV1SMYD3CRBNNPC1PKM
	SCHEMBL29899567	0.86	BACE1 (0.56)	TRPV1SMYD3CRBNNPC1PKM
	SCHEMBL395950	0.86	TRPV1 (0.59)	TRPV1CRBNPTPN1NPC1RAB9A
	SCHEMBL9375259	0.82	RARB (0.55)	HDAC1HDAC3PTPN1PLAUNPC1
	SCHEMBL18006544	0.80	EPHX2 (0.54)	SMYD3CRBNHDAC1HDAC3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.