Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31140485 | 1.00 | MAT2A (0.43) | MAT2AKMOP2RX7DRD1MAPT | |
| SCHEMBL31140490 | 0.86 | MAT2A (0.43) | MAT2AP2RX7DRD1MAPTDOT1L | |
| SCHEMBL31140492 | 0.86 | MAT2A (0.43) | MAT2AP2RX7DRD1MAPTDOT1L | |
| SCHEMBL22093957 | 0.83 | KDM4E (0.45) | MAPTTP53KDM4EHTTSMN1; SMN2 | |
| SCHEMBL31145623 | 0.83 | KDM4E (0.45) | MAPTTP53KDM4EHTTSMN1; SMN2 | |
| SCHEMBL31140488 | 0.82 | MAT2A (0.40) | MAT2AP2RX7DRD1MAPTDOT1L | |
| SCHEMBL31361093 | 0.81 | MAT2A (0.39) | MAT2AP2RX7DRD1MAPTDOT1L | |
| SCHEMBL26487792 | 0.79 | MAT2A (0.42) | MAT2AP2RX7PDE2APDE10A | |
| SCHEMBL31140483 | 0.76 | MAT2A (0.35) | MAT2ADOT1LPDE2A | |
| SCHEMBL22094106 | 0.75 | MEN1 (0.52) | MAT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118900841-A | Tricyclic compounds and uses thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2024-11-05 | — | — | CN | disclosed |