Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31140487 | 0.82 | MAT2A (0.43) | MAT2APDE2ADRD1P2RX7KDM4E | |
| SCHEMBL31140485 | 0.82 | MAT2A (0.43) | MAT2APDE2ADRD1P2RX7KDM4E | |
| SCHEMBL31140492 | 0.82 | MAT2A (0.43) | MAT2APDE2ADRD1P2RX7KDM4E | |
| SCHEMBL31140490 | 0.82 | MAT2A (0.43) | MAT2APDE2ADRD1P2RX7KDM4E | |
| SCHEMBL30736400 | 0.81 | MAT2A (0.44) | MAT2ATYMSPDE2AP2RX7KDM4E | |
| SCHEMBL31140482 | 0.79 | MAT2A (0.46) | MAT2AP2RX7 | |
| SCHEMBL31361093 | 0.76 | MAT2A (0.39) | MAT2APDE2ADRD1P2RX7KDM4E | |
| SCHEMBL31140483 | 0.76 | MAT2A (0.35) | MAT2APDE2ADOT1LMEN1KMT2A | |
| SCHEMBL22103537 | 0.74 | KDM4E (0.44) | KDM4EMAPTHTTMEN1PSMD14 | |
| Hydrochloric Acid SCHEMBL31361058 | 0.73 | MAT2A (0.34) | MAT2APDE2ADRD1KDM4EDOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118900841-A | Tricyclic compounds and uses thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2024-11-05 | — | — | CN | disclosed |