Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25228664 | 1.00 | DDB1 (0.43) | DDB1CRBNPDE9AKMT2AKDM4E | |
| SCHEMBL16452781 | 0.86 | KMT2A (0.42) | DDB1CRBNPDE9AKMT2AKDM4E | |
| SCHEMBL29852305 | 0.86 | KMT2A (0.42) | DDB1CRBNPDE9AKMT2AKDM4E | |
| SCHEMBL16452775 | 0.83 | PPARD (0.40) | DDB1CRBNPDE9AKMT2AKDM4E | |
| SCHEMBL28131310 | 0.83 | ALOX5AP (0.43) | DDB1CRBNPDE9AKMT2AKDM4E | |
| SCHEMBL25647216 | 0.81 | PPARD (0.42) | DDB1CRBNPDE9AKMT2AKDM4E | |
| SCHEMBL30851289 | 0.79 | HTR2C (0.57) | KMT2A | |
| SCHEMBL13197446 | 0.79 | LIPE (0.41) | DDB1CRBNPDE9AKMT2AKDM4E | |
| SCHEMBL5471696 | 0.79 | HTR2C (0.57) | KMT2A | |
| SCHEMBL13197445 | 0.79 | LIPE (0.41) | DDB1CRBNPDE9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118696050-A | Spirocyclic cyclic modulators of cholesterol biosynthesis and their use for promoting remyelination | 基因泰克公司 | 2024-09-24 | — | — | CN | disclosed |