⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1124238 | 0.97 | GABRP (0.59) | — | |
| SCHEMBL265217 | 0.97 | — | — | |
| SCHEMBL264824 | 0.97 | — | — | |
| SCHEMBL27394 | 0.97 | — | — | |
| SCHEMBL1913403 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL8829491 | 0.94 | — | — | |
| SCHEMBL11690150 | 0.94 | — | — | |
| Methylamine SCHEMBL6691699 | 0.92 | GABRP (0.61) | — | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL7932482 | 0.87 | GABRP (0.50) | — | |
| Levulinic Acid SCHEMBL165683 | 0.85 | LMNA (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988186-A | Beta-lactamase inhibitor | 维纳拓尔斯制药公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-106687465-B | β -lactamase inhibitor | 维纳拓尔斯制药公司 | 2019-04-16 | — | — | CN | disclosed |
| EP-2267133-B1 | METHOD FOR MAKING POLY(3-HYDROXYPROPRIONATE) | CJ RES CENTER LLC (US) | 2017-07-12 | — | — | EP | disclosed |
| CN-103113226-B | Tert-butyl Methacrylate class monomer and polymkeric substance, preparation method and use | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-08-05 | — | — | CN | disclosed |
| CN-103113226-A | Tert-butyl methacrylate monomer and polymer, synthesis method and application thereof | SHANGHAI INST ORGANIC CHEM | 2013-05-22 | — | — | CN | disclosed |
| US-8093022-B2 | polylactones produced in biological system selected from bacteria, yeasts, fungi and plants, expressing enzymes selected from polyhydroxyalkanoate synthase, acyl-CoA transferase and hydroxyacyl CoA transferase, and hydroxyacyl CoA synthetase | METABOLIX, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-7968325-B2 | Expression vector comprising nucleotide sequences coding polyhydroxyalkanoic acid synthase for use in preparing intracellular polyesters for use in agriculture, medicine and plastics preparation | METABOLIX, INC. (US) | 2011-06-28 | — | — | US | disclosed |
| EP-2267133-A2 | Method for making poly(3-hydroxyproprionate) | METABOLIX, INC. (US) | 2010-12-29 | — | — | EP | disclosed |
| EP-1078068-B1 | POLYHYDROXYALKANOATE BIOPOLYMER COMPOSITIONS | METABOLIX INC (US) | 2010-09-29 | — | — | EP | disclosed |
| US-20080275208-A1 | POLYHYDROXYALKANOATE BIOPOLYMER COMPOSITIONS | METABOLIX, INC. DELAWARE | 2008-11-06 | — | — | US | disclosed |
| EP-0958367-B1 | METHODS FOR THE BIOSYNTHESIS OF POLYESTERS | METABOLIX INC (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20040253693-A1 | Methods for the biosynthesis of polyesters | METABOLIX, INC. | 2004-12-16 | — | — | US | disclosed |
| US-6759219-B2 | COMPRISES COEXPRESSION OF POLYHYDROXYALKANOIC ACID SYNTHASE (VIA ALCALIGENES) AND FATTY ACID ACYL-COA TRANSFERASE/ SYNTHETASE (VIA CLOSTRIDIUM) | METABOLIX, INC. | 2004-07-06 | — | — | US | disclosed |
| US-20040033572-A1 | Polyhydroxyalkanoate biopolymer compositions | METABOLIX, INC. | 2004-02-19 | — | — | US | disclosed |
| US-20030113884-A1 | METHODS FOR THE BIOSYNTHESIS OF POLYESTERS | CJ CHEILJEDANG CORPORATION (KR) | 2003-06-19 | — | — | US | disclosed |
| US-6323010-B1 | PROVIDING SUBSTRATES WHICH COMPRISE 2-HYDROXYBUTYRIC ACID IN BIOLOGICAL SYSTEM WHICH IS GENETICALLY ENGINEERED TO EXPRESS ONE OR MORE ENZYMES SELECTED FROM THE GROUP CONSISTING OF POLYHYDROXYALKANOATE SYNTHASE, ACYL-COA TRANSFERASE, ETC. | METABOLIX, INC. | 2001-11-27 | — | — | US | disclosed |
| EP-1078068-A2 | POLYHYDROXYALKANOATE BIOPOLYMER COMPOSITIONS | METABOLIX, INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999061624-A2 | POLYHYDROXYALKANOATE BIOPOLYMER COMPOSITIONS | METABOLIX, INC. (US) | 1999-12-02 | — | — | WO | disclosed |
| EP-0958367-A1 | METHODS FOR THE BIOSYNTHESIS OF POLYESTERS | MONSANTO COMPANY (US) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998039453-A1 | METHODS FOR THE BIOSYNTHESIS OF POLYESTERS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |