Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 5/20 | 0.44 |
| ▸ | GART | P22102 | 1/20 | 0.40 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.39 |
| ▸ | SLC46A1 | Q96NT5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25294982 | 0.85 | TYMS (0.40) | TYMSDHFRGART | |
| SCHEMBL25257994 | 0.85 | TYMS (0.40) | TYMSDHFRGART | |
| SCHEMBL31143686 | 0.84 | DHFR (0.54) | TYMSDHFR | |
| SCHEMBL24344795 | 0.78 | TDP1 (0.36) | DHFR | |
| SCHEMBL31476915 | 0.78 | DHFR (0.56) | TYMSDHFR | |
| SCHEMBL25725125 | 0.77 | TYMS (0.41) | TYMSDHFRGART | |
| SCHEMBL24344797 | 0.77 | TYMS (0.36) | TYMSDHFRGART | |
| SCHEMBL25294343 | 0.77 | TYMS (0.36) | TYMSDHFRGART | |
| SCHEMBL24343434 | 0.77 | TYMS (0.39) | TYMSDHFRGARTFOLR1 | |
| SCHEMBL24343391 | 0.76 | TYMS (0.39) | TYMSDHFRGART |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118613484-A | Antifolate linker-drug and antibody-drug conjugates | 拜奥迪斯私人有限公司 | 2024-09-06 | — | — | CN | disclosed |