SCHEMBL31145083

SCHEMBL31145083

Oc1ccccc1-c1c2ccccc2cc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.55
TRPM4 Q8TD43 1/20 0.50
NQO2 P16083 1/20 0.48
CYP1A2 P05177 2/20 0.48
CES1 P23141 1/20 0.47
SOS1 Q07889 1/20 0.44
HSD17B1 P14061 1/20 0.43
HSD17B2 P37059 1/20 0.43
ALDH1A1 P00352 5/20 0.43
HPGD P15428 5/20 0.43
HSD17B10 Q99714 3/20 0.43
BCL2L1 Q07817 1/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
KDM4E B2RXH2 3/20 0.42
MAPT P10636 3/20 0.42
MPI P34949 1/20 0.42
RIPK1 Q13546 1/20 0.42
CYP2C19 P33261 3/20 0.42
GLA P06280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7176241 1.00 ALOX5 (0.55) ALOX5TRPM4NQO2CYP1A2CES1
SCHEMBL702189 0.84 HPGD (0.52) CYP1A2ALDH1A1HPGDHSD17B10BCL2L1
SCHEMBL701570 0.84 CES1 (0.55) ALOX5TRPM4NQO2CYP1A2CES1
SCHEMBL27839602 0.82 ALOX5 (0.55) ALOX5TRPM4NQO2CYP1A2HSD17B1
SCHEMBL12786270 0.82 NQO1 (0.46) ALOX5TRPM4NQO2CYP1A2CES1
SCHEMBL11977700 0.81 ALOX5 (0.58) ALOX5TRPM4NQO2CYP1A2CES1
SCHEMBL6403846 0.81 NSD2 (0.54) CYP1A2ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL4252546 0.79 ESR2 (0.43) ALOX5TRPM4NQO2CYP1A2CES1
SCHEMBL4458241 0.79 ALOX5 (0.51) ALOX5TRPM4NQO2CYP1A2ALDH1A1
SCHEMBL4264384 0.79 CES1 (0.50) ALOX5TRPM4NQO2CYP1A2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4617737-A2 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-09-17 EP disclosed
US-20250223400-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-07-10 US disclosed
EP-4506392-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-02-12 EP disclosed
CN-118786109-A Novel 1, 3-bis (1-methyl-1-phenylethyl) benzene compound 本州化学工业株式会社 2024-10-15 CN disclosed