SCHEMBL4458241

SCHEMBL4458241

Cc1ccc(O)c(-c2c3ccccc3cc3ccccc23)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.51
TDP1 Q9NUW8 4/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
MAPT P10636 3/20 0.51
GAA P10253 2/20 0.51
USP2 O75604 2/20 0.51
HPGD P15428 2/20 0.51
ALOX15 P16050 2/20 0.51
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
LMNA P02545 1/20 0.51
POLB P06746 1/20 0.51
HSD17B10 Q99714 1/20 0.51
THRB P10828 1/20 0.43
TRPM4 Q8TD43 1/20 0.42
GPR84 Q9NQS5 1/20 0.42
TRPA1 O75762 1/20 0.42
CYP2A6 P11509 2/20 0.41
CYP1A2 P05177 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28813393 0.88 HSP90AA1 (0.52) TDP1MEN1KMT2AMAPTGAA
SCHEMBL14327803 0.85 MEN1 (0.48) ALOX5TDP1MEN1KMT2AMAPT
SCHEMBL2703913 0.85 THRB (0.50) TDP1MEN1KMT2AMAPTGAA
SCHEMBL27839602 0.81 ALOX5 (0.55) ALOX5MEN1KMT2AMAPTHPGD
SCHEMBL7176241 0.79 ALOX5 (0.55) ALOX5MEN1KMT2AMAPTHPGD
SCHEMBL31145083 0.79 ALOX5 (0.55) ALOX5MEN1KMT2AMAPTHPGD
SCHEMBL10586899 0.79 MEN1 (0.52) ALOX5TDP1MEN1KMT2AMAPT
SCHEMBL29690328 0.79 TDP1 (0.51) TDP1MEN1KMT2AMAPTGAA
SCHEMBL14423570 0.79 TDP1 (0.51) TDP1MEN1KMT2AMAPTGAA
SCHEMBL11977700 0.77 ALOX5 (0.58) ALOX5MEN1KMT2AMAPTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7479531-B2 Copolymer of ethylene and/or propylene; and octen-1-ol,7-octen-1-ol trimethylsilyl ether, octenyl acetate, 5-norbornen-2-yl acetate, 5-norbornen-2-ol and/or 5-norbornen-2-ol trimethylsilyl ether; transition metal catalyst comprising 2-arylazo- or 2-arylphosphazo- phenoxide ligand EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-01-20 US disclosed
EP-1709087-B1 OLEFIN POLYMERIZATION CATALYST SYSTEM EXXONMOBIL CHEM PATENTS INC (US) 2008-09-03 EP disclosed
US-7285609-B2 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-23 US disclosed
EP-1626976-B1 OLEFIN POLYMERIZATION CATALYST SYSTEM EXXONMOBIL CHEM PATENTS INC (US) 2007-10-17 EP disclosed
EP-1626999-B1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS EXXONMOBIL CHEM PATENTS INC (US) 2007-09-26 EP disclosed
US-20070197751-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. 2007-08-23 US disclosed
EP-1709087-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2006-10-11 EP disclosed
US-7094848-B2 Olefin polymerization catalyst system EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-08-22 US disclosed
US-7045583-B2 Olefin polymerization catalyst system EXXON MOBIL CHEMICAL PATENTS INC. (US) 2006-05-16 US disclosed
EP-1626999-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS Exxonmobil Chemical Patents Inc. (US) 2006-02-22 EP disclosed
EP-1626976-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM Exxonmobil Chemical Patents Inc. (US) 2006-02-22 EP disclosed
WO-2005068514-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-07-28 WO disclosed
US-20050137367-A1 Olefin polymerization catalyst system EXXONMOBIL CHEMICAL PATENTS INC. 2005-06-23 US disclosed
US-20040260043-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS, INC. 2004-12-23 US disclosed
WO-2004101634-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-11-25 WO disclosed
WO-2004101576-A1 OLEFIN POLYMERIZATION CATALYST SYSTEM EXXONMOBIL CHEMICAL PATENTS INC (US) 2004-11-25 WO disclosed
US-20040230015-A1 Olefin polymerization catalyst system EXXONMOBIL CHEMICAL PATENTS INC. 2004-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040230015-A1 Olefin polymerization catalyst system OXER1, NR4A1, AP2S1 ALOX5 77/4885TDP1 3932/4885MEN1 2613/4885
US-20050137367-A1 Olefin polymerization catalyst system HCCS, CBR3, RAD54L ALOX5 1042/4885TDP1 3444/4885MEN1 4262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.