Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24364369 | 1.00 | PIK3CD (0.33) | PIK3CDNOS3NOS1NOS2 | |
| SCHEMBL24366781 | 0.78 | FFAR1 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL24233949 | 0.78 | FFAR1 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL24365301 | 0.76 | DYRK1A (0.43) | — | |
| SCHEMBL25322868 | 0.73 | CYP2A6 (0.37) | NOS3NOS1NOS2 | |
| SCHEMBL25322871 | 0.73 | CYP2A6 (0.37) | NOS3NOS1NOS2 | |
| SCHEMBL24365547 | 0.71 | NOS3 (0.41) | NOS3NOS1NOS2 | |
| SCHEMBL24233803 | 0.70 | IDH1 (0.38) | NOS3NOS1NOS2 | |
| SCHEMBL25322604 | 0.70 | IDH1 (0.38) | NOS3NOS1NOS2 | |
| SCHEMBL25323858 | 0.68 | NOS3 (0.38) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078117-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS INC (US) | 2026-03-19 | — | — | US | disclosed |
| US-20240279219-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279219-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | PIK3CD 4481/4885NOS3 556/4885NOS1 619/4885 |
| US-20260078117-A1 | COMPOUNDS AND METHODS OF USE | NR3C2, ADRA1A, CNR1 | PIK3CD 3800/4885NOS3 2054/4885NOS1 1666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.