Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.40 |
| ▸ | IGF1R | P08069 | 3/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22094011 | 1.00 | MAT2A (0.47) | MAT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31145399 | 0.82 | MAT2A (0.57) | MAT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL22093132 | 0.82 | MAT2A (0.57) | MAT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL22093267 | 0.79 | MAT2A (0.46) | MAT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31145405 | 0.79 | MAT2A (0.46) | MAT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6639554 | 0.79 | MAT2A (0.46) | MAT2AKDM4EALDH1A1HPGDADORA2A | |
| SCHEMBL22094368 | 0.78 | MAT2A (0.46) | MAT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL22093125 | 0.78 | MAT2A (0.49) | MAT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31145323 | 0.78 | MAT2A (0.46) | MAT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31145263 | 0.78 | MAT2A (0.49) | MAT2AKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528824-A | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-113166078-B | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2024-11-19 | — | — | CN | disclosed |