Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 10/20 | 0.55 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22093178 | 1.00 | MAT2A (0.55) | MAT2AC5AR1ALDH1A1KDM4EGLA | |
| SCHEMBL22093318 | 0.85 | MAT2A (0.42) | MAT2AC5AR1ALDH1A1KDM4EGLA | |
| SCHEMBL31145596 | 0.85 | MAT2A (0.42) | MAT2AC5AR1ALDH1A1KDM4EGLA | |
| SCHEMBL22093440 | 0.85 | MAT2A (0.64) | MAT2AALDH1A1KDM4EHPGDKLK7 | |
| SCHEMBL29570934 | 0.85 | MAT2A (0.64) | MAT2AALDH1A1KDM4EHPGDKLK7 | |
| SCHEMBL22103151 | 0.83 | MAT2A (0.49) | MAT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL31145547 | 0.81 | MAT2A (0.69) | MAT2A | |
| SCHEMBL22093969 | 0.81 | MAT2A (0.69) | MAT2A | |
| SCHEMBL31145360 | 0.77 | MAT2A (0.45) | MAT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL22093456 | 0.77 | MAT2A (0.45) | MAT2AALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528824-A | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-113166078-B | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2024-11-19 | — | — | CN | disclosed |