Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22093456 | 1.00 | MAT2A (0.45) | MAT2AALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL22094709 | 0.83 | MAT2A (0.44) | MAT2AALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL31145598 | 0.83 | MAT2A (0.44) | MAT2AALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL22103537 | 0.81 | KDM4E (0.44) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL22093235 | 0.80 | MAT2A (0.69) | MAT2AALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL29570284 | 0.80 | MAT2A (0.69) | MAT2AALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL31145596 | 0.78 | MAT2A (0.42) | MAT2AALDH1A1KMT2ALMNAGLA | |
| SCHEMBL22093318 | 0.78 | MAT2A (0.42) | MAT2AALDH1A1KMT2ALMNAGLA | |
| SCHEMBL31145341 | 0.77 | MAT2A (0.55) | MAT2AALDH1A1TSHRGLAKDM4E | |
| SCHEMBL22093178 | 0.77 | MAT2A (0.55) | MAT2AALDH1A1TSHRGLAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528824-A | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-113166078-B | 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors | 伊迪亚生物科学有限公司 | 2024-11-19 | — | — | CN | disclosed |