Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | RXRB | P28702 | 3/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3121853 | 0.87 | MAPT (0.44) | NR1H4EPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL3118521 | 0.84 | ALDH1A1 (0.39) | TSHRTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL3126646 | 0.79 | ALDH1A1 (0.35) | TSHRALDH1A1HSD17B10 | |
| SCHEMBL3124942 | 0.79 | ESR1 (0.44) | TP53TSHRMEN1CYP1A2KMT2A | |
| SCHEMBL3108654 | 0.79 | ALDH1A1 (0.56) | CYP1A2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3127822 | 0.77 | LMNA (0.48) | TP53TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL3121762 | 0.77 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3118620 | 0.77 | TSHR (0.44) | TSHRTDP1CA1CA2ALDH1A1 | |
| SCHEMBL103563 | 0.77 | SRD5A2 (0.57) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL9449169 | 0.77 | ALDH1A1 (0.59) | SRD5A2RARBRARGNR1H4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732645-B2 | Aromatic vinyl ether compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-08 | — | — | US | disclosed |
| EP-2161248-A1 | Aromatic vinyl ether compounds | Daicel Chemical Industries, Ltd. (JP) | 2010-03-10 | — | — | EP | disclosed |
| US-7518021-B2 | Aromatic vinyl ether compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20090088592-A1 | AROMATIC VINYL ETHER COMPOUNDS | IWAHAMA TAKAHIRO | 2009-04-02 | — | — | US | disclosed |
| US-20040181098-A1 | Aromatic vinyl ether compounds | EMORY UNIVERSITY | 2004-09-16 | — | — | US | disclosed |
| EP-1413568-A2 | Aromatic vinyl ether compounds | Daicel Chemical Industries, Ltd. (JP) | 2004-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181098-A1 | Aromatic vinyl ether compounds | SUV39H2, SUV39H1, RAVER1 | SRD5A2 787/4885RARB 645/4885RARG 372/4885 |
| US-20090088592-A1 | AROMATIC VINYL ETHER COMPOUNDS | SUV39H2, SUV39H1, RAVER1 | SRD5A2 698/4885RARB 315/4885RARG 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.